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Anatomy of My Mind for the New Year

head, face, nose, mouth, lips, bones, skull, x-ray, radiology

“A Better Future?” 

X-rays are used to projects things of the mind and  feelings that go deep into the bones.  The X-ray of the front of the head looks upward and forward to the future.  This art piece was  created for the New Year of  2016 with a hope of deep introspection for  each thoughtful person to improve themselves and the world.   As the year 2015 has now come to a close, we all hope for a better future.  This is not going to be a passive inheritance from thin air.  It will require deep introspection and reflection.   The art piece shows the head of a person, taking the first step to self realisation and fulfilment – raising the question.  The need for a thorough mental review of the past and the future is an absolute necessity.  The importance of playing an active role in personal destiny is emphasised by asking the first question – ‘A Better Future? ?” implying – How do I do I get involved with my own destiny and the destiny of my family and the people close to me?  The  X-ray is used to project a feeling that goes deep into the bones.  The X-ray of the front of the head looks upward and forward to the future.

The New Year fills the mind with all sorts of thoughts and feelings about oneself and the world.  It is a time to take stock of the state of the union of the self!  There is always room for growth and improvement.

Deep reflection and introspection is needed in order to accomplish this growth.  Life is a struggle and a wrestle for all at multiple levels.  There are physical, emotional, psychological, mental and spiritual aspects.  Each person must deal with their own failures and successes.  Sometimes what seems or seemed like a failure is in fact a success.

Life is a struggle and a wrestle for all at multiple levels.  There are physical, emotional, psychological, mental and spiritual aspects.  Each person must deal with their own failures and successes.

 

Who am I, what am I, and who do I want to be?

Perhaps the wisest advice I received was from an egoistic professor of surgery who suggested that one should project oneself to the age of 80 and then look back and see if one accomplished what one really wanted to accomplish.  Was it money, power, or personal fame or did it have to do with fulfilling relationships?  Are there things of the body that I should have or could have done?  Are there things of the mind that I could have or should have done?  Are  there things of the soul that I could have or should have done?

head, bones, skull, X-ray, radiology, introspection, nose, chin

The First Reflection for the New Year

 In this art piece, X-rays are used to project a feeling that goes deep into the bones.  The  X-ray on the right shows a forward gaze of a person with well defined facial features. The image on the left is modified to show a blank reflection.  The art shows the head of a person, looking in the mirror at the end of the year and wondering about the past and the future.  The first  reflection is blank since the experience of  the past year and the future are difficult to grasp in that short moment.  Nothing more than the blank is expected .  Persistence and honesty with a continued effort is needed to progress beyond this point. The stare into the mirror should be more than momentary.

This art piece was also created for the new year of  2016 with a hope of deep introspection of each thoughtful person to improve themselves and the world.

 

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“What Do I Need?” 

X-rays are used to project a deep and honest questioning as to what is really needed .  The X-ray of the right head looks upward and forward to the future. The response of excessive material wealth for show is the response in this instance  One has to decide if this dream is directed toward self fulfillment.  Showing off the prize in the hope of an egotistical victory in competition with others in the community is the passion of this person.

On second thoughts-  What do I really need?

Improving my body

head, mind, bones, protection, food, physiology

Absolutes of Life

As the year 2015 has now come to a close,, a deep search is needed – right down to the core to preserve life.    Survival is the first requirement. Protection, food, and water are absolutes.  Protection means a roof and walls to keep the threatening elements out.  Food and water means nutrition and fluid to maintain bodily function

The art piece shows the head of a person, pursuing the most basic needs.  The pursuit and acquisition of basic needs is the first step.  Although this is logical to all and everybody, the new generation forget that the first step to independence, is physical independence that requires an ability to support the most basic needs of life.  It is a lesson to communities and countries who owe this basic need to their people.  It is also a lesson to individuals who pursue personal happiness as they enter”real life” after they have been educated.   The home is a simple rustic log cabin heated by a fire.

 

Improving My Mind  –  Where do I start?

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“Anatomy of Brain Function; Receive, Process, Produce, Export” 

shows the bare skeleton of the human brain function.  The brain receives, processes, and exports.  The complexity of these three basic functions will unfold not only in the brain but in all functional systems.  The style is reminiscent of surrealism . The complexity of brain function is reduced to its 3 major functions.

So a good place to start is to a focus on the sensory system and it so happens that Janus of January has a lesson to share!

head, brain, eyes, ears, nose, mouth, sight, hearing taste, touch, smell, X-ray, Janus

Janus in Touch with His Senses

Janus is the God of beginnings and transitions and the art piece emphasises the organs of his senses.  He is usually depicted with two heads, one facing forward to the future and the other back to the past. The month of January takes its name from the Roman god.  As we face the new year, respect for the miracle of our senses needs to be celebrated.  In line with our resolutions of the optimizing the body, taking full advantage of our senses to optimise our mind is a natural progression.  The sensory organs keep us in touch with all that is around us, and it behoves us to use these miraculous tools  to feed our mind.  The art piece shows the sensory organs including, the eyes (sight), ears (hearing), nose (smell), mouth (taste), nose (smell), and hands (touch).

This art piece asks you to …see when you look, listen when you hear, taste when you eat….feel when you touch..

 As the year 2015 has come to a close, we all hope for a better future.  This is not going to be a passive inheritance from thin air.  It will require deep introspection and reflection of real and meaningful needs.    X-rays are used to project a deep and honest questioning as to what is really needed .  The X-ray of the left head of Janus looks upward and forward to the future with senses perked. The right head of Janus looks back with senses heightened in similar fashion.  

So a good place to start is an intense focus on the basics

Absolutes of food, water, and a home ….before the pie in sky

Use the senses sensibly – See when you look, listen when you hear, taste when you eat, remember to smell….and feel when you touch..

 

 

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Anatomy of the Hands in December

Anatomy of the Hands in Black and White of December

The hands have a story to tell of December! Here in the Northern hemisphere, winter has started to set in and it brings a sense of doom, darkness, and cold.

In its naked form, the doom translates into two opposing colors in their extreme: black and white. Nights are long and days are frequently adorned with the white of snow.  The vista is bleak.

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“Colors of Winter” 

is a minimalist portrayal of the season.  The black reflects the long dark nights and the white reflects the snow.  Artistic portrayal of the season is in its most basic form.  Black has many attributes, and in this context, reflects loneliness, quiet, mystery, but also intimidation.  The absence of light prevents us from seeing things, and the inability to see things makes us nervous.  At its most extreme it reflects death.  On the other hand, black is a color of authority and power.  Night is the end of the day, but as soon as light appears, a new day awakens.  White also has many characteristics and is the confluence of all color, resulting in no color at all.  At its best it signifies purity.  On a cold winter morning after a snowfall there is a white silence as if the world is asleep.  

 

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“Reality of Black and White in Winter” 

Spring colors are long gone.  The greens of summer and the yellows of fall have disappeared. Skeletons of the large deciduous trees stand naked in the cold.

We have lived with the bleak and cold winters for centuries.  As a result, we have devised ways to counter this barren vista. Using our heads and hands, we have learned to bring light, color, and warmth to December.

Festivals of light have been created through both ancient and modern cultures including  Christmas, Chanukah, Kwanzaa, Bodhi day, Malh festival, Mōdraniht, Saturnalia, Sol Invictus, Yule, Yolda, Sadeh, and Chahar Shanbeh Suri.  Universal among these cultural celebrations is the need to bring joy, warmth, and light to offset the dark’s gloom.

Hands play a large part in the December season.  In a literal sense, they reach out to friends and family, light candles and fires, and extend uplifting gestures by providing food, gifts, and hugs.  In a spiritual way, they extend in hope and prayer.

This post tells the story of the hands in December in symbolic and abstract ways by combining photography, radiology, and painting.

In this extreme rendering of the middle of a cold winter night, the heavens are black and the earth is white with snow.  Only the stars of the heaven provide glimpses of warmth and light.

hands, bones, cold night, tree, X-ray, winter

Cold Hands Looking for Light and Warmth 

shows x-rays of cold, skeletal hands in the adverse conditions of freezing winter among naked branches, in a field of snow. The nighttime scene with a full moon adds a mysterious and eerie ambience.  The art piece expresses a desperation of a group of people when they are suffering and searching for light and warmth.  The open hands are chilled to the bone, pleading for special empathy.  The moon provides neither warmth nor light, but offers a glimmer of hope, however small.  The X-rays are used to strip the flesh down to the bones and the common suffering of a community is rendered real and deeply palpable.  This piece has a surreal character, since the x-rays are taken out of context and placed into snow white fields.  The hands have been brought together to look like a tree.

The limited warmth and light provided by the moon is temporary. Since the cycle of time brings a new day and new vista, there is an honored promise for a new beginning, accompanied by the sun which is brighter and warmer than the moon.

hands, hand, bones, phalanges, X-ray. radiology, winter, cold, sunrise, sun, warmth

Cold Hands – Warmth and Light with Tincture of Time  

shows x-rays of the skeleton of hands warmed by the light and heat of sunrise. The hands greet the sun with open arms. In this early morning scene, the whole tree of hands lays open like a flower to the newfound warmth.  The piece expresses relief after an arduous night, and a promise by the light of the moon of better things to come. 

winter, snow, cold, trees, hands, bones, xrays

Giving Hands in the Snow” 

shows x-rays of hands in the adverse conditions of the cold winter among naked branches of the trees, in a field of snow.  With the warmth of the sun, the hands are bold enough to face the winter. The foreground (recent past) is shaded and dark while the future is bright, light, and blue. The hands are chilled to the bone but their upward and upright position reflect strength, a “high 5”, a wave, or a handshake.  As the hands assume boldness, light emerges and projects into the future.

During the cold month of December hands also reach out to others.

hands, charity, bones, light, candle, charity, giving, receiving

You Get What You Give 

shows hands that give and receive.  This gesture relates to moral justice. There is a balance in our actions.  This balance is not always evident nor provided in material currency.  The teacher receives this satisfaction from a look in the eye of a student who suddenly understands. The policeman or fireman receives the same grateful look that words cannot replace. It is given and received in love and compassion and is the essence of bonding. This feeling occurs between both people and animals.  The art piece shows “giving” hands and “receiving” hands.  The receiving hands are tipped to both receive and to give in the continuing cycle.  The X-rays are used to strip the flesh down to the bones and make the charity tangible.  The candle is the light and warmth that results from the the interaction of giving and receiving.  The message is particularly poignant in the winter season when we are driven indoors in dark, cold and often lonely days.  We need the light and the bonds to help us survive the dark days.

Festivals of light including Chanukah and Christmas are festivals when light and human bonds are needed and are abundant.

 

hands, light, warmth, candles, lighting, Chanukah

“Hand Lighting Chanukah Candles” 

shows a hand warmed by the light and heat created with the lighting of the Chanukah candles. The nighttime scene adds an ambience of spirituality.  The art piece expresses hope of enlightenment for the world.  In the candle lighting ritual, the primary candle is called the Shamash and it is lit first, and is then used to light the others starting from left to right.  Shamash was also the Sun God in Mesopotamiathe god of justice in Babylonia and Assyria and shemesh means sun in Hebrew.  All of these historical associations involve the casting of light and warmth, both physical and spiritual.  The candles are based in a simple chanukiah of stone and clay.

 

hand, hands, Christmas, Jesus Christ, nativity, Mary, moon, star, birth, body language

“Birth of Jesus – Welcoming Hands ” 

Christmas is the season of welcoming the birth of Jesus Christ to the world.  As the progenitor of the Christian faith he brought and continues to bring tolerance, compassion, and respect for life to the world.  Artistic portrayal of the event shows welcoming hands of the future Christian world.  Darkness for many was illuminated by the event. In this art piece, the bright moon (almost as bright as any sun) lights up the black of the night.  The star of Bethlehem has a mysterious and unique blue hue directing the 3 kings or wise men to the event.  Black and white are used liberally in this work.  Though opposites in many ways, they also compliment and need each other to reflect the contrast of moods.  

Acknowledgement:  The central component of “Birth of Jesus – Welcoming Hands” depicting Jesus and Mary was adapted from the public domain work of  Gerard van Honthorst  (1592-1656) entitled “Adoration of the Shepherds.”

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Diverse Hands of Spirituality

shows hands progressing to a bonding position in prayer and contemplation.  At the pinnacle, a light is created and reflects on the water.  X-rays are used to project a feeling that goes deep into the bones.  The colors express our outside differences, but we are all made of the same flesh and bones.  A triangle with the apex reflects a direction and an upward focus to a heightened physical and spiritual  position.  This art piece is created for Christmas 2015 with a hope of mutual respect among all faiths.

During this season there should be time for contemplation.

hands, bones, fire, X-ray, warmth, winter

“Cold Hands Warmed by Fireside Chat” 

shows x-rays of skeletal hands warmed by the light and heat of the fire. This piece expresses relief after a trudge through the cold snowy night to find light and warmth.  The hands hold the warm fire at a distance but seem tender in the way they cherish the comfort and the fire, freeing the body from physical discomfort and allowing time for introspection.

And as a world … what do we see?

The  year of 2015 has turned humanity on its head, particularly concerning is the rise of extreme Muslim ideologies in which belief and faith are placed above human life.  The rise of antisemitism is palpable.  The immorality of double standards where political and economical bias reigns above the truth is shameful.

The next art piece is an appeal to our leaders to talk and put life and truth above all.

 

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Bones of Many Hands Speaking to Each Other

“How can we hold each other rather than kill each other?”
they asked.
“We all seem to be made of the same stuff” they said as they looked inside themselves.

The AiA rendering is a collection of the diagnostic X-rays of many hands of people of various ages, in various positions of giving and taking and in health and disease.  The hand with the watch epitomizes the concept of time.  Cultural aspects are also suggested.  The hand with a wedding band provides a sense of trust and faith and the hand with the Claddagh ring represents love loyalty and friendship. The hands are oriented to give the sense that they are communicating with each other.

Since December also brings in the New Year, it is time to try and make changes for a brighter 2016.  We cannot predict, but we can hope:

hand, hands, hope, peace, body language,

“Hands of Hope for a Better New Year” 

shows hands held together with hope, warmed by the dim light and heat of the moonlight.  2015 was not an easy year and created a heavy heart for many who witnessed and experienced senseless killing. The nighttime scene lends a sense of spirituality but also of uncertainty.  The piece above shows hands scarred by the year’s events.  They are held not in prayer but in a gentle pose that reflects hope for the New Year of 2016. We hope that sanity and not hatred rules.  We pray for leadership that is free from double standards, and that is committed to common decency.

Hope is passive; the initiation of action should be a simple first step. The honest handshake between trusting partners is the least we should expect.

 hands, handshake, trust, bond

The Handshake

Let us agree that the right to live is above all other rights!

“In joined hands there is still some token of hope, in the clinched fist none.”
― Victor Hugo, The Toilers of the Sea

“You cannot shake hands with a clenched fist.”
― Indira Gandhi

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Hermit of the Abdomen – Dedication to The Pancreas

The Hermit of the Abdomen – History of the Anatomy of the Pancreas 

O’ Dear Pancreas

You have been called the hermit of the abdomen
By whom I do not know
But in your dark and hidden way, you have
Spoken without a word
From the gurgling depths of the abdomen
Yes – you have earned this lonely title
and a coin should be tossed
to the person who coined the phrase
But it took a long time to understand who this hermit was – and what he was doing in the darkness of the abdomen

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Can You see the Zebra-like  Pancreas in the Dark of the Abdomen?

From the day of antiquity
You have been looked upon by many
Herophilus, the father of anatomy had the first incisive insights into you
As he was one of the very few who had the guts to explore the guts in open fashion

Sanzio_01_Plato_Aristotle wikib

Aristotle (384 BC -322 BC)

(extracted from a painting by Raphael)

Aristotle at the same time seemed to have known something about you
but then you lay unharmed and unexplored for almost 500 years
Until Rufus mistook you for a piece of meat –
You must have laughed at the “pan kreas” thing
How wrong he was – you evasive little trickster

And then the Talmud – always seeming to be right
thought you were the finger of the liver –
little did they know how independent you were

While Vesalius was up to your “hide and seek” game

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Vesalius (1514-1564)

the magical eyes of da Vinci missed you completely
even though he saw the serpiginous splenic artery snake right above you

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The Serpiginous Splenic Artery Above the Pancreas

(da Vinci – 1452-1519)

The splenic artery which lies above the pancreas was described by da Vinci

but by the time the dissection took place the pancreas had autolysed and therefore was not seen by the genius da Vinci.

Your ducts seemed to have intrigued the next generation Wharton Wirsung and de Graaf
as you sustained the pain of the quill penetrating your inner gut
(I forget you were already dead but it must of hurt just watching!)
A little later it was that man called Vater and the little Italian Santorini who found your minor duct and your nipple
And so by this time we had a good understanding of you in your nakedness
but of course, as said – you were dead

And so young Bernard explored your factories, and got a sense of your canine workings,
But you were able to hold on to your sweet secret for just a little longer
until the Langerhans found the family jewels in the famous 2% of your population-
The islets – those beautiful eyelits – governess of all things sweet in the body

InsulinIHC

Islets of Langerhans

(Paul Langerhans 1847-1888)

Eberle, Bernard, Danilevsky, and Kuhne joined up across the world to expose your antacid and enigmatic enzymatic brew
And once again your wonderful workings for a better world were exposed –
and we knew then, that you were the quiet and effective type –
a hermit who did good
but did not want the limelight

To see you as you lived and breathed in the flesh
was the mission of Wilhelm the X-Ray man
who crusaded the path to visualise 40,000 Angstroms under the skin
And then there was a slew of heroes who learned to slew your sickened parts – including the famous Whipple who was able to Whipple you in an inimitable way

And then a bone guy – for God’s sakes – a bone guy! – called Banting and his student Best
exposed the insular chemistry of you insulin that had given you the power over the sweet
Never mind – in the end it was for the good of all –
And a new era was borne

C._H._Best_and_F._G._Banting_ca._1924

Best and Banting

(Charles Best 1899- 1978  Frederick Banting 1894- 1941  )

And with the advent of ultrasound, CT, MRI, and endoscopy

You came out and were a hermit no more

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Coming Out Party in the Abdomen for the Pancreas 

And so we try to understand your form as our scans explore you as you live and breathe
and we stare in awe at your odd shape – why oh why did you choose that shape?
What are you supposed to look like? – we have no clue
And we are happy – so happy for you that you are well nourished by a double blood supply

Blood-supply-of-the-pancreas

Blood Supply of the Pancreas

And we wonder why you have no skin – we thought all the organs had a skin
except for your tail – almost a foreskin
And you are off axis on two planes – what is that all about? – kinda crooked
And your twin origins and the intimacy with the duodenum, of the ventral twin
And the strange fusion of the Wirsung guy excluding the little Italian Santorini
It seems to me that your matrimonial fusion with Wirsung and the bile duct has led to more problems than the merger was worth
It does not seem in the long run, to have been a marriage made in heaven
What was that all about? Is there a grand plan to come

And so we try to understand your diseases
And in some way we understand that the guy glugging down the bottle
Could be punished by your reaction
But why Oh why are you so nasty to those whose misfortune it is to have stones roll down and get no satisfaction.. down the green vile bile route
Have you not learned to live with the green secretion by now
And did you not know that by reacting the way you do, that you are cutting off your nose to spite you head?

While type 2 seems remote from you
We don’t know about this Type 1 business
Why are you made to suffer so much at the hands of your own body on your own body
We feel sorry for you – to have your own buddies reject you – must be awful
And then to see so many young ones suffer because you don’t work
We once again see and understand what power you control from that deep dark hermit home of yours

And the cancer thing … so silently it creeps on you causing your collagen to counter
Only making things worse as it strangles nerve, blood vessel, and your spouse duct – the green one, – without regard

And then I think of you in your prime and in your happiness
When you are with your two buddies – the splenic vein and the renal vein
And you all look so much alike, and happy swimming in that deep ocean where you hide
And I wish this was forever

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So Happy Swimming Your Buddies Splenic Vein and Renal Vein

by Ashley Davidoff MD – copyright 2015

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Modified from previous publication in TheCommonVein.com

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Art of Anatomy of the Pancreas

Art of Anatomy of the Pancreas

Introduction

Ashley Davidoff MD Copyright 2015

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Pancreas in the Sky

is a photograph that shows a cloud formation embodying the shape of a pancreas

The anatomy of the pancreas is unusual and the physiology is multifaceted.  It is  a gland and is part of both the digestive and hormonal systems of the body.  Structurally it is characterised by its unusual shape and position and the absence of a capsule.  Functionally it is involved in the digestion of food as well as in the metabolism of glucose.  The most common diseases include pancreatitis, pancreatic carcinoma and diabetes. Serum tests, ultrasound, CT scan, MRI and endoscopy are most commonly used in diagnosis of pancreatic disease.  Treatment options include medical treatment (eg insulin in type 1 diabetes) minimally invasive procedures, and surgery.

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“Pancreas in Pink” 

is artwork derived from a CT scan and shows the upper abdominal cavity with the pancreas in bright pink surrounded by the liver, gallbladder, and kidneys. The aorta and inferior vena cava are the major transport vessels and serve to connect the organs.

Structure

Unusual Shape

“…and we stare in awe at your odd shape – why oh why did you choose that shape?
What are you supposed to look like? – we have no clue”  

from  “Hermit of the Abdomen” 

anatomy of pancreas

Shapes of the Pancreas

The pancreas has been compared to many objects including an elongated comma on its side, an elongated number 9 on its side, a prism, a banana, an inverted and curved upside down tobacco pipe, and even an old fashioned revolver. Placing a seahorse or a woodpecker with head down and tail up probably brings us closest to the complex shape of the pancreas. The objects used for description are so varied and disparate, that one wonders if we truly have a grasp of the shape of this organ. A more practical way to look at the shape of the organ is to define the shape of its component parts.

Structure – Position

Deep in the Abdomen in the Retroperitoneum

The pancreas lies in the anterior pararenal space of the retroperitoneum surrounded by a vertebral body and kidneys posteriorly, the liver and gall bladder to its right, the spleen to its left, and the stomach and left lobe of the liver in front.  This AiA rendering shows the pancreas cycling through the seasons.  In the  spring it is in shades of  pink, the summer in blue, the fall in  red, and in the winter in ice blue and white. 

Function

The pancreas has dual functions in the the metabolism of the body.  It acts as an as both an exocrine gland (secretes into ducts) and an endocrine gland (secretes into the circulation).

As an exocrine gland it secretes enzymes into ducts that lead to the duodenum.  These enzymes aid in the digestion of fat, proteins, and carbohydrates. As an endocrine gland it is a key player in the control of glucose metabolism which it accomplishes by secreting insulin into the circulation.

The acini are the microscopic glands making up 98% of the parenchyma and they function as the exocrine component.

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“Blueberries of the Glands of the Pancreas”

is a rendering of the histological appearance of the pancreatic acinar glands. The artpiece  illustrates the ductules that subtends the acini  which are the exocrine glandular cells. The shape of the acinar cells and ductules are reminiscent of grapes or berries on a stalk.

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“Histology of the Glands of the Pancreas”  

The exocrine hormones of the pancreas that aid in the digestion of fats, proteins and carbohydrates are produced in the acinar cells in the glandular unit called the acinus.  The art piece shows the acinus with acinar cells and the duct that transports the secretions to the pancreatic duct and eventually to the duodenum where they aid in the digestion of proteins fats and carbohydrates.

The islets of Langerhans secrete insulin into the blood stream, very soon after ingestion of a meal in order to control blood sugar and intracellular glucose concentrations. The endocrine cells called the islets of Langerhans represent only 1-2% of the tissue volume of the pancreas, but play a vital role in body function and well being. They are most numerous in the tail of the pancreas.

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Islets of Langerhans

Immunohistochemistry on mouse pancreas for insulin shows the brown stained Islets of Langerhans that secrete insulin among the acinar cells.  They represent only 2% of the population of pancreatic cells. 

(Modified  Image –  Courtesy  Billyboy Wikipedia Public Domain)

Diseases

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Acute Necrotic Pancreatitis

This is a CT of an elderly man who had severe pancreatitis.  Within the retroperitoneum there is necrotic pancreas (asterisk).  It is enlarged and consists mostly of air (arrow), fluid, and high density hemorrhagic components.  The findings are consistent with a gangrenous pancreatic abscess.  The surgeon noted that the pancreas looked and smelled like a “dead fish…. that had been dead for quite a long time.”  Other structures including the gallbladder(gb), liver, kidneys, spleen and stomach surround the pancreas

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Pancreatic Cancer with Spread to the Liver

The CT scan shows a primary pancreatic cancer (red asterisk) with metastases to the liver.  Four of many metastases are identified with white asterisks

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Normal Pancreatic Cells and Pancreatic Cancer Cells

In the upper image the cellular makeup of the acinar cells of the pancreas manifest with a normal nuclear to cytoplasmic ratio reflecting the relative size of the nucleus to the cytoplasm.   The 2nd image show cancerous cells of the exocrine pancreas.  The blue nuclii are far too large for the amount of the cytoplasm of the cell (abnormal nuclear to cytoplasm ratio).  The malignant cells are also too dark (hyperchromatic) and lack uniformity and organization.  These are all features of malignant cells .  Cancerous cells do not obey the rules of the body and  have no regard for the body at large. Malignant cells are equivalent to rebels in the community. They destroy and do not contribute to the wellbeing of the society.  They also invade the territory of neighboring structures.

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Ravages of Diabetes 

The foot of a person with diabetes following amputation of the 2nd, 3rd, and 4th digits as a result of poor circulation of the tissues.  The magnified view shows the calcification and hardening of the arteries. 

Diagnosis

“Doppler Ultrasound of the Pancreas-Hermit of the Abdomen”

shows the pancreas in black in front of the splenic vein

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“ERCP – Ductal Skeleton of the Pancreas”

is from an ERCP with an injection into normal the dorsal pancreatic duct of Wirsung with contrast also noted in the distal common bile duct

“Arteries of the Pancreas”

is from an angiogram of the celiac axis and shows the multiple arteries that supply the pancreas.  The head of the pancreas is supplied by the  superior pancreatico-duodenal vessels which arises from the gastroduodenal artery,  and inferior pancreatico-duodenal artery which arises from the SMA.  The body is supplied by the splenic artery and the superior mesenteric artery.

Treatment

Treatment options include medical treatment (eg insulin in type 1 diabetes) minimally invasive procedures for drainage and relief of obstruction, and surgery.

Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute b

3D Nuclear Magnetic Resonance Structure  of Insulin Dimer

(Modified from public domain image from Wikipedia and Courtesy Jawahar Swaminathan Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute) 

“And then a bone guy – for God’s sakes – a bone guy! – called Banting and his student Best
exposed the insular chemistry of your insulin that had given you the power over the sweet
Never mind – in the end it was for the good of all –
And a new era was born 

from “Hermit of the Abdomen” Davidoff

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Pancreas and Buddies

This aquatic scene shows the relationship of the pancreas to its neighbours particularly the splenic vein and left renal vein which run a parallel course, almost like a bunch of buddies romping in the water.  The arching bodies with heads all in the same direction is quite beautiful

And then I think of you in your prime and in your happiness
When you are with your two buddies – the splenic vein and the renal vein
And you all look so much alike, and happy swimming in that deep ocean where you hide
And I wish this was forever”

from “Hermit of the Abdomen” Davidoff

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